An altercation between two men turned violent when one of the men shot and killed the other several times, San Antonio Police said.
Police said the suspect, Christopher Bustos, shot the victim, Gumesindo Gonzales, multiple times in the chest and fled the scene in a vehicle.
The incident took place around 3:45 a.m. Sunday in the 1700 block of Point West near Palo Alto College on the south side.
Gonzales, 36, died after being taken to San Antonio Military Medical Center in critical condition.
Authorities said Bustos knew Gonzales. Bustos has since been charged with murder.